| 沈昱含,万坤铭,蔡孟成,等.基于数据挖掘的中医药治疗盆腔静脉淤血综合征用药规律研究[J].浙江中医药大学学报,2021,45(4):378-383. |
| 基于数据挖掘的中医药治疗盆腔静脉淤血综合征用药规律研究 |
| Study on Medication Law of Traditional Chinese Medicine Treatment of Pelvic Congestion Syndrome Based on Data Mining |
| DOI：10.16466/j.issn1005-5509.2021.04.012 |
| 中文关键词: 盆腔静脉淤血综合征 中医药疗法 外治法 疗效评价 用药规律 数据挖掘 |
| 英文关键词: pelvic congestion syndrome therapy of traditional Chinese medicine external therapy curative effect evaluation medication law data mining |
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| 中文摘要: |
| [目的]分析中医药治疗盆腔静脉淤血综合征(pelvic congestion syndrome，PCS)的用药规律，为中医药临床诊治PCS提供依据。 [方法]检索1994年1月至2019年6月Sinomed、Pubmed、中国知网(China National Knowledge Infrastructure，CNKI)、维普、万方数据库中以中医药治疗PCS的相关研究文献，采用SPSS 21.0统计软件，分别对药物频次、药类、性味、归经进行频次分析，得出PCS用药在文献中的大致分布规律。[结果]根据文献检索策略，经过筛选和排除动物实验和重复研究，最终纳入83篇相关研究文献。口服给药频次前6位的中药依次为当归、川芎、延胡索、丹参、赤芍及桃仁，药物功效频次前4类的为活血化瘀药、补益药、清热药及理气药；外治法给药频次前6位中药依次为丹参、赤芍、桃仁、延胡索、当归及三棱，药物功效频次前4类的依次为活血化瘀药、清热药、补益药及解表药。两种给药方法的中药四气分布温性均多于寒性，五味分布前3位是苦、辛、甘，归经前4位均是肝经、脾经、心经、肾经。[结论]在用药特点上，治疗PCS最常用的中药为当归、丹参、赤芍、延胡索；治法上，主要采用活血祛瘀法，同时重视扶正，辨证运用清热、理气、解表等治法。 |
| 英文摘要: |
| [Objective] To analyze the medication law of traditional Chinese medicine(TCM) treatment of pelvic congestion syndrome(PCS)， and to provide the basis for the diagnosis and TCM treatment of PCS in clinic. [Methods]To search relevant PCS research and literature of TCM treatment in Sinomed， Pubmed， China National Knowledge Infrastructure(CNKI)，China Science and Technology Journal Database(VIP) and WanFang database(from Jan. 1994 to Jun. 2019). SPSS 21.0 statistical software was used to analyze the drug frequency， category， property， taste， channel tropism， in order to obtain the general distribution rules of PCS drug use in the literature. [Results]According to the strategy of literature retrieval， after the animal experiments and repeated studies were screened and excluded， totally 83 related literatures were included. For oral medicine， the first six drugs in frequency were Radix Angelica Sinensis， Rhizoma Chuanxiong，Rhizoma Corydalis， Radix Salviae Miltiorrhizae， Radix Paeoniae Alba and Semen Persicae; the top four drugs efficacy frequencies were blood circulation promoting and blood-stasis removing drugs， tonifying drugs， heat clearing drugs and Qi regulating drugs. For enema， the first six drugs in frequency were Radix Salviae Miltiorrhizae， Radix Paeoniae Alba， Semen Persicae， Rhizoma Corydnlis， Radix Angelica Sinensis and Rhizoma Sparganii; the top four drugs efficacy frequencies were blood circulation promoting and blood-stasis removing drugs， heat-clearing drugs， tonifying drugs and exterior syndrome resolving drugs. In both two modes of administration， warm was more than cold in the distribution of four natures， the top three of five flavors were bitter， pungent and sweet， the top four meridians were liver， spleen， heart and kidney. [Conclusion]In medication characteristics， Radix Angelica Sinensis， Radix Salviae Miltiorrhizae， Radix Paeoniae Alba and Rhizoma Corydalis are the most commonly used drugs. The method of promoting blood circulation and removing blood stasis has played an important role in the treatment of PCS; at the same time， importance was attached to strengthen the body and uses the methods of clearing away heat， regulating Qi and resolving exterior symptoms according to syndrome differentiation. |
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