| [Objective] Discussion on the clinical experience of Ephedra in the treatment of urticaria starting from etiology and pathogenesis. [Methods] Combined with the ancient books of TCM, the experience of modern doctors and the author's clinical experience, this paper expounds the thinking and experience of Ephedra in the treatment of urticaria from the aspects of the pathogenesis of urticaria, the main efficacy of Ephedra and clinical medical cases. [Results] Urticaria is mainly caused by the invasion of various evils, which leads to the disharmony between Ying-wei and the closing of Xuanfu. The key to the pathogenesis of urticaria is that the ying-wei is closed. The treatment of urticaria is to open striae and expel evils. Ephedra is good at inducing diaphoresis. In clinic, we often treat urticaria with ephedra, which has a good effect. [Conclusion] Ephedra’s properties are pungent-warm,which is good at opening striae expelling evils. It can be used skillfully in clinic, and its clinical effect is considerable. |