文章摘要
愈痤汤联合光电协同技术治疗肺经风热型轻中度寻常痤疮的临床疗效及安全性观察
Clinical efficacy and Safety of Yucuo decoction combined with Emax in the treatment of mild to moderate Acne Vulgaris syndrome of Wind-Heat in Lung Meridian
投稿时间:2021-01-28  修订日期:2021-04-19
DOI:
中文关键词: 肺经风热型  愈痤汤  光电协同技术  轻中度寻常痤疮  疗效  安全性
英文关键词: syndrome of wind-heat in lung meridian  Yucuo decoction  Emax  mild to moderate acne vulgaris  efficacy  safety
基金项目:温州市医药卫生科研项目(2019ZB010)
作者单位邮编
史华洁 温州市中医院 
蒋越 温州医科大学附属第一医院 325000
梁文丽 温州市中医院 
麻晓玲 温州市中医院 
郑明警 温州市中医院 
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中文摘要:
      [目的]探究愈痤汤联合光电协同技术(Emax)治疗肺经风热型轻中度寻常痤疮的临床疗效及安全性。[方法]选取2019年4月~2020年3月符合诊断标准的150例肺经风热型轻中度寻常痤疮患者并按照随机数字表法分为5组,依据不同的治疗方案进行分组,具体分为愈痤汤联合Emax组(中药+光电组)、愈痤汤组(中药组)、Emax组(光电组)、常规治疗组(西药组)、常规治疗联合Emax组(西药+光电组)各30例,分别对5组治疗前和治疗4周后的GAGS评分、中医证候评分及不良反应进行记录并统计分析。[结果]中药+光电组、中药组、光电组、西药组、西药+光电组的总有效率分别为96.67%(29/30)、83.33%(25/30)、70.00%(21/30)、76.67%(23/30)、80.00%(24/30)(P<0.05)。5组治疗后较治疗前GAGS评分、中医证候评分均显著降低(P<0.01)。在皮疹改善程度方面,中药+光电组均优于对照4组(P<0.05);在中医证候改善方面,中药+光电组在皮疹痒痛、颜面潮红、口渴喜饮、舌苔证候中均明显优于对照4组(P<0.01)。5组在尿黄、便秘、舌质证候中差异无明显统计学意义(P>0.05)。5组均无明显不良反应发生。[结论]针对肺经风热型轻中度寻常痤疮,愈痤汤联合光电协同技术治疗可获得显著疗效,且无明显不良反应,值得临床推广应用。
英文摘要:
      [Objective]To explore the clinical efficacy and safety of Yucuo decoction combined with Electro-Optical Synergy (Emax) in the treatment of mild to moderate acne vulgaris syndrome of wind-heat in lung meridian.[Methods]From April 2019 to March 2020, 150 patients with mild to moderate acne vulgaris syndrome of wind-heat in lung meridians were selected and randomly divided into 5 groups according to different treatment schemes. They were divided into Yucuo decoction combined with Emax group (traditional Chinese medicine + photoelectricity group), Yucuo decoction treatment group (traditional Chinese medicine group). Emax group (photoelectricity group), routine treatment group (western medicine group) and routine treatment combined with Emax group (western medicine + photoelectricity group). The GAGS score, TCM syndrome score and adverse reactions of the five groups before and 4 weeks after treatment were recorded and statistically analyzed.[Results]The total effective rates of traditional Chinese medicine + photoelectricity group, traditional Chinese medicine group, photoelectricity group, western medicine group and western medicine + photoelectricity group were 96.67% (29/30), 83.33% (25/30), 70.00% (21/30), 76.67% (23/30) and 80.00% (24/30) (P<0.05), respectively. The scores of GAGS and TCM syndrome in the 5 groups after treatment were significantly lower than those before treatment (P<0.01). The improvement degree of skin rash in the traditional Chinese medicine + photoelectric group was better than that in the control group 4 (P<0.05). And in the improvement of TCM syndromes, the traditional Chinese medicine + photoelectric group was significantly better than the control group in itching pain, facial redness, thirst and liking and tongue coating syndrome (P<0.01). There was no significant difference in yellow urine, constipation and tongue syndrome among the five groups (P>0.05). There were no obvious adverse reactions in the five groups.[Conclusion]For mild to moderate acne vulgaris syndrome of wind-heat in lung meridian, Yucuo decoction combined with photoelectric synergistic technology can obtain significant curative effect. And there is no obvious adverse reaction, so it is worth popularizing and applying in clinic.
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