| 唐志铭,丁继存,荆梦晴,等.白藜芦醇软膏治疗病理性瘢痕的临床疗效研究[J].浙江中医药大学学报,2019,43(1):57-60. |
| 白藜芦醇软膏治疗病理性瘢痕的临床疗效研究 |
| Clinical Efficacy of Resveratrol Ointment in the Treatment of Pathological Scars |
| DOI：10.16466/j.issn1005-5509.2019.01.012 |
| 中文关键词: 白藜芦醇软膏 病理性瘢痕 增生性瘢痕 疙瘩 温哥华瘢痕量表 临床疗效 |
| 英文关键词: resveratrol ointment pathological scar hypertrophic scar keloid Vancouver scar scale clinical efficacy |
| 基金项目:徐州市医学青年后备人才项目[徐卫科教(2015)7号] |
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| 中文摘要: |
| [目的] 探讨白藜芦醇软膏治疗病理性瘢痕的临床疗效。[方法] 将68例病理性瘢痕患者随机分为治疗组和对照组，每组各34例。治疗组外用白藜芦醇软膏，对照组外用美宝疤痕软膏，分别于皮肤瘢痕部位外涂，每日早晚各涂一次，使用周期为90d。两组治疗前后均进行温哥华瘢痕量表(Vancouver scar scale， VSS)评分，治疗结束后进行临床疗效判定。[结果] 治疗后两组患者VSS评分均低于治疗前，差异有统计学意义(P＜0.05)；治疗后组间比较，治疗组VSS评分低于对照组，差异有统计学意义(P＜0.05)；治疗组VSS评分降低程度高于对照组(P＜0.05)；治疗组总显效率为87.75%，高于对照组总显效率68.08%，差异有统计学意义(P＜0.05)。[结论] 白藜芦醇软膏有较好的祛除瘢痕作用，未发现任何不良反应，不失为一种安全有效的祛瘢产品。 |
| 英文摘要: |
| [Objective] To investigate the clinical efficacy of resveratrol ointment in the treatment of pathological scars. [Methods] Sixty-eight patients with pathological scars were randomly divided into treatment group and control group, 34 cases in each group. On the skin scar area, patients in two groups separately coated with resveratrol ointment and MEBO scar ointment twice a day morning and evening, for the period of 90 days. Both groups were scored by the Vancouver scar scale(VSS) before and after treatment, and clinical efficacy evaluation was performed after treatment.[Results] After treatment, the VSS scores of the scars in both groups decreased, there was significance difference, compared with pretreatment(P＜0.05), but the VSS scores of the scars in treatment group were significantly lower than those in control group, the difference was statistically significant(P＜0.05). The total effective rate of treatment group was significantly better than that of control group, and there was statistical significance(P＜0.05).[Conclusion] Resveratrol ointment has a good effect of removing scars and no adverse reactions have been found. It is a safe and effective remove scar product. |
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