文章摘要
刘琉,王洁宜,冯波,等.干燥综合征伏风致病病机及治法探讨[J].浙江中医药大学学报,2022,46(3):340-344.
干燥综合征伏风致病病机及治法探讨
Discussion on the Pathogenesis and Treatment of Sjogren's Syndrome Based on Hidden Wind
DOI:10.16466/j.issn1005-5509.2022.03.021
中文关键词: 干燥综合征  伏风  病因病机  祛风扶正  破瘀拔毒  平熄内风  风毒  风药
英文关键词: Sjogren's syndrome  hidden wind  etiology and pathogenesis  dispelling wind and supporting healthy Qi  dissolve blood stasis and remove toxin  calming endogenous wind  wind toxin  wind-dispelling herb
基金项目:国家自然科学基金项目(82074341)
作者单位
刘琉 浙江中医药大学第二临床医学院 杭州 310053 
王洁宜 浙江中医药大学第二临床医学院 杭州 310053 
冯波 浙江中医药大学第二临床医学院 杭州 310053 
周东海 浙江中医药大学附属第二医院 
张旭峰 浙江中医药大学第二临床医学院 杭州 310053 
王新昌 浙江中医药大学附属第二医院 
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中文摘要:
      [目的] 从伏风角度探讨干燥综合征(Sjogren's syndrome,SS)的病因病机与中医治疗,以期更全面地认识SS,扩宽临床诊治思路,提高临床疗效。[方法] 从伏风理论的源流,风伏于五脏六腑、四肢百骸等部位而致病的过程等方面探讨伏风致病的病因病机,并结合伏风致病规律对SS的治法及用药进行论述。[结果] 伏风最初源于伏邪理论,清朝刘吉人对伏风发挥最多,认为伏风可藏于孔窍、肌表、血脉及肺脾肾等脏腑,伏而化燥、动血、化瘀、成毒,并可引动内风,相兼致病,而出现类似于SS的表现,诸如口眼干燥、紫癜、泄泻、水肿等。临床论治伏风所致的SS,可从扶正兼以理气、破瘀合以拔毒等角度入手,予祛除内风、活血化瘀、益气解毒等药物。 [结论] 伏风理论对SS的诊疗具有重要的临床意义,根据伏风致病的过程及特点等角度来认识SS,能更全面地探究SS的本质,为治疗SS提供新思路和方法。
英文摘要:
      [Objective] To explore the etiology, pathogenesis and treatment of Sjogren's syndrome (SS) by traditional Chinese medicine from the perspective of hidden wind, in order to have a more comprehensive understanding of SS, broaden clinical diagnosis and treatment ideas, as well as improve clinical efficacy. [Methods] Discuss the etiology and pathogenesis of hidden wind according to the origin of hidden wind theory, that the pathogenic process of wind hidden in the viscera, limbs and related parts of the body, etc, combining with hidden wind‘s pathogenic law to conclude the treatment and medication of SS. [Results] Generally speaking, the hidden wind arised from the theory of hidden pathogen. LIU Jiren in the Qing Dynasty applied it most, who believed that hidden wind could be hidden in the orifices, muscle surface, blood vessels, lungs, spleen and kidneys, etc, leading internal dryness, blood boiling, stasis, and finally became toxins, inducing endogenous wind at the same time, finally resulted in disease, which was similar to SS, such as drying mouth and eyes, purpura, diarrhea, edema and so on. The clinical treatment of SS caused by hidden wind can start from the perspectives of supporting healthy Qi and regulating Qi, dispelling blood stasis and removing toxins, and herbs of dispelling endogenous wind, activating blood circulation and dissipating blood stasis, and replenishing Qi and removing toxins can be used. [Conclusion] The theory of hidden wind has important clinical significance for the diagnosis and treatment of SS. Understanding SS from the perspective of the pathogenic process and characteristics of hidden wind can more comprehensively explore the essence of SS and provide new ideas and methods for the treatment of SS.
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