| 尤焱南,任丽顺,赵霞.降气平哮方治疗儿童哮喘外寒内热证120例疗效观察[J].浙江中医药大学学报,2022,46(4):433-438, 450. |
| 降气平哮方治疗儿童哮喘外寒内热证120例疗效观察 |
| Observation of Therapeutic Efficacy of Jiangqi Pingxiao Decoction on Treatment of 120 Cases of Asthma in Children with External Cold and Internal Heat Syndrome |
| DOI：10.16466/j.issn1005-5509.2022.04.015 |
| 中文关键词: 降气平哮方 哮喘发作 外寒热内证 痰气相搏 疗效观察 伏风 中医药 儿童 |
| 英文关键词: Jiangqi Pingxiao decoction asthma in attack external cold and internal heat syndrome intersection of phlegm and Qi observation of therapeutic efficacy hidden wind traditional Chinese medicine children |
| 基金项目:江苏省中医药领军人才项目(SLJ0224)；江苏高校优势学科建设工程资助项目、南京中医药大学中医学优势学科三期项目开放课题(ZYX03KF48)；江苏省研究生科研创新计划项目(KYCX21_1676) |
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| 中文摘要: |
| [目的] 观察降气平哮方治疗儿童哮喘发作期外寒内热证的临床疗效及其安全性。 [方法] 采用前瞻性自身前后对照研究方法，纳入2018年5月至2020年12月就诊的哮喘发作期患儿120例，给予降气平哮方并根据病情结合西医常规治疗，疗程2周。采用证候量表评价哮鸣、气喘等症状改善情况，并如实记录药物相关不良反应。[结果] 治疗1周后总有效率87.5%，治疗2周后总有效率97.5%。降气平哮方治疗1周后，哮鸣、喘息、咳嗽、痰液、胸闷等主症单项评分及总评分均显著降低，与治疗前比较，差异有统计学意义(P＜0.01)，治疗2周后，效果更佳；治疗1周后，与治疗前比较，次症中鼻塞流涕、咽喉充血、夜寐等评分差异显著，治疗2周后，大便、舌苔评分治疗差异有统计学意义(P＜0.01)。 [结论] 降气平哮方能改善哮喘发作期哮鸣、喘息、咳嗽、咳痰、胸闷等主要症状，且安全性好。 |
| 英文摘要: |
| [Objective] To observe the clinical efficacy and safety of Jiangqi Pingxiao decoction in the treatment of asthma in children with external cold and internal heat syndrome. [Methods] Using a prospective self-control case study method， 120 patients with asthma exacerbations who attended the clinic from May 2018 to December 2020 were included and given Jiangqi Pingxiao decoction combined with conventional western medicine according to their conditions for a 2-week treatment course. Syndrome scale was used to evaluate the relief of symptoms such as wheezing and asthma， and truthfully record drug-related adverse reactions. [Results] The total effective rate was 87.5% after 1 week of treatment and 97.5% after 2 weeks of treatment. After 1 week of treatment with Jiangqi Pingxiao decoction， the individual and total scores of the main symptoms such as croup， wheezing， cough， sputum and chest tightness were significantly reduced， and the difference was statistically significant compared with that before treatment(P＜0.01)， and the effect was better after 2 weeks of treatment. Compared with before treatment， the scores of nasal obstruction， runny nose， throat congestion and night sleep were significantly different after 1 week of treatment， and the scores of stool and tongue coating were significantly different two weeks after treatment(P＜0.01). [Conclusion] Jiangqi Pingxiao decoction can relieve the main symptoms of asthma attacks such as croup， wheezing， cough， sputum and chest tightness， and has a good safety profile. |
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