| 郭滢,谢冠群,范永升2(指导).范永升教授运用青蒿治疗SLE临床经验[J].浙江中医药大学学报,2022,46(8):831-834. |
| 范永升教授运用青蒿治疗SLE临床经验 |
| Professor FAN Yongsheng‘s Experience in Treating Systemic Lupus Erythematosus with Artemisia Annua |
| DOI：10.16466/j.issn1005-5509.2022.08.002 |
| 中文关键词: 青蒿 系统性红斑狼疮 病案 解毒祛瘀滋阴方 蒿芩清胆汤 中医临床 名医经验 范永升 |
| 英文关键词: Artemisia annua SLE medical record Jiedu Quyu Ziyin Recipe Haoqin Qingdan Decoction clinical practice of traditional Chinese medicine experience of famous doctor FAN Yongsheng |
| 基金项目:浙江省自然科学基金项目(LY20H270005) |
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| 中文摘要: |
| [目的] 总结全国名中医范永升教授运用青蒿治疗系统性红斑狼疮(systemic lupus erythematosus，SLE)的临床经验，提高对SLE的认识。[方法] 通过跟师学习，收集范教授诊治的SLE患者的临床资料，以及整理医案、查询相关文献，回顾分析范教授在SLE的不同阶段运用青蒿及并配伍相关药物的临床经验，并以验案佐证。[结果] 范教授通过辨证论治，以青蒿之清热解毒，治疗SLE轻型阴虚兼有热毒证；以青蒿之透邪滋阴，治疗SLE轻型余邪内伏证；以青蒿之清胆理气，治疗SLE重型肝郁血瘀证。所举病案中分别以解毒祛瘀滋阴方及蒿芩清胆汤治疗轻型及重型SLE，治疗后患者症状改善，SLE疾病活动(systemic lupus erythematosus disease activity index，SLEDAI)评分降低。[结论] 范教授针对SLE的不同阶段，运用青蒿清透虚热、凉血除蒸、解暑截疟，并配伍相关药物，疗效显著，其经验值得推广学习。 |
| 英文摘要: |
| [Objective] To summarize the clinical experience of Professor FAN Yongsheng in the treatment of systemic lupus erythematosus(SLE) with Artemisia annua and improve the understanding of SLE. [Methods] Through learning from the teacher， collecting the clinical data of SLE patients treated by Professor FAN， sorting out the medical records， querying the relevant literature， Professor FAN‘s clinical experience in the use of Artemisia annua and related drugs in different stages of SLE were reviewed and analyzed. Medical cases were presented as proof. [Results] Through syndrome differentiation and treatment， Professor FAN treats mild SLE of Yin deficiency and heat-toxin with Artemisia annua to clear away heat and toxic material; treats mild SLE of residual evil with Artemisia annua to disperse evil and nourish Yin; and treats severe SLE of liver depression and blood stasis with Artemisia annua to cleargallbladder and regulate Qi. The mild and severe SLE patients in medical cases were treated with Jiedu Quyu Ziyin Recipe and Haoqin Qingdan Decoction respectively. After treatment， the symptoms of the patients were relieved and the systemic lupus erythematosus disease activity index(SLEDAI) scores decreased. [Conclusion] According to different stages of SLE， Professor FAN uses Artemisia annua to clear away deficiency heat， cooling blood and eliminating steaming， relieving summer heat and intercepting malaria， combined with related drugs， the curative effect is remarkable， and his experience is worth popularizing and learning. |
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