| 刘斯妤,郭凯,沈湘晴,等.基于数据挖掘探析肖和印治疗儿童上气道咳嗽综合征用药规律[J].浙江中医药大学学报,2023,47(3):317-323. |
| 基于数据挖掘探析肖和印治疗儿童上气道咳嗽综合征用药规律 |
| Analysis on Medication Rule of Professor XIAO Heyin for Children Upper Airway Cough Syndrome Based on Data Mining |
| DOI：10.16466/j.issn1005-5509.2023.03.018 |
| 中文关键词: 儿童上气道咳嗽综合征 数据挖掘 用药规律 古今医案云平台 中医药 用药特点 临床经验 肖和印 |
| 英文关键词: children upper airway cough syndrome data mining medication rules Ancient and Modern Medical Records Cloud Platform traditional Chinese medicine medication characteristics clinical experience XIAO Heyin |
| 基金项目:北京市科学技术委员会首都临床特色应用研究与成果推广项目(Z171100001017109)；中国中医科学院科技创新工程-重大攻关项目课题(CI2021A02507) |
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| 中文摘要: |
| [目的] 基于古今医案云平台进行数据挖掘，分析肖和印教授治疗儿童上气道咳嗽综合征(upper airway cough syndrome，UACS)的用药特点，探讨其用药规律，以期为儿童UACS的治疗提供临床思路。 [方法] 以2019年1月1日至2022年1月1日中国中医科学院望京医院儿科肖和印教授门诊诊治的UACS病案为数据来源，将病案资料录入Excel 2018软件，建立数据库并规范术语，通过古今医案云平台进行数据挖掘，探讨其用药规律。[结果] 共纳入病案245则，纳入处方245首，涉及中药149味，排名前10的中药频次从高到低分别为桔梗、炙百部、蜜紫菀、甘草、玄参、射干、板蓝根、浙贝母、陈皮、蝉蜕，药性以寒性、微寒、平和温为主，五味偏苦、甘、辛和酸，主要归肺经、胃经和肝经。关联规则分析获得蜜紫菀-炙百部、炙百部-桔梗等多组核心中药组合。肖和印教授的核心处方为:蜜紫菀、炙百部、桔梗、甘草、玄参、射干、板蓝根、陈皮、蝉蜕、钩藤、浙贝母、荆芥、瓜蒌。[结论] 肖和印教授治疗儿童UACS，以宣肺化痰、止咳平喘、利咽通窍为主，兼顾解表散邪、祛风解痉，具有寒温并用、宣降共施、肺胃同调的特点。 |
| 英文摘要: |
| [Objective] To analyze the characteristics of Professor XIAO Heyin，s medication for children upper airway cough syndrome(UACS) based on Ancient and Modern Medical Records Cloud Platform and explore the rule of medication， in order to provide clinical ideas for the treatment of children UACS. [Methods] The medical records of children UACS in the Outpatient Department of Pediatrics of Professor XIAO Heyin of Wangjing Hospital， China Academy of Chinese Medical Sciences from January 1， 2019 to January 1， 2022 were taken as the data source. The medical records were input into Excel 2018 software， the database was established and the terminology was standardized. Data mining was conducted through the Ancient and Modern Medical Records Cloud Platform to explore the medication rules. [Results] A total of 245 cases and 245 prescriptions were included in this study， and 149 Chinese herbs were involved. The top 10 Chinese herbs in frequency from high to low were Platycodon grandiflorum， Radix stemonae， Aster tataricus L.f.， Glycyrrhiza uralensis Fisch.， Radix scrophulariae， Belamcanda chinensis， Radix isatidis， Fritillaria thunbergii， Citri Reticulatae Pericarpium and Periostracum Cicadae. The herbs were mainly cold， slightly cold， mild and warm taste， and the five tastes were bitter， sweet， spicy and sour， which mainly belong to the lung meridian， stomach meridian and liver meridian. Multi group core Chinese herbs combinations such as Aster tataricus L.f.-Radix stemonae and Radix stemonae-Platycodon grandiflorum were obtained. The core prescriptions to obtain Professor XIAO Heyin were: Aster tataricus L.f.， Radix stemonae， Platycodon grandiflorum， Glycyrrhiza uralensis Fisch.， Radix scrophulariae， Belamcanda chinensis， Radix isatidis， Citri Reticulatae Pericarpium， Periostracum Cicadae， Uncaria rhynchophylla， Fritillaria thunbergii， Nepeta cataria L.， Fructus Trichosanthis. [Conclusion] Professor XIAO Heyin，s treatment of children UACS mainly focuses on promoting the lung and reducing phlegm， relieving cough and asthma， invigorating the pharynx and dredging the orifices， combined with dispelling exterior pathogenic factors， dispelling wind and relieving spasmolysis， and has the characteristics of combining cold and warm， combining dispersing and reverting， and regulating the lung and stomach at the same time. |
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