| 王蔚玲,张永军,叶林茂,等.从玄府探肺癌之病机及叶天士“辛味”理论在其辨治中的意义[J].浙江中医药大学学报,2023,47(12):1406-1412. |
| 从玄府探肺癌之病机及叶天士“辛味”理论在其辨治中的意义 |
| Exploring the Pathogenesis of Lung Cancer from Xuanfu and Its Corresponding Syndrome Differentiation and Treatment Based on YE Tianshi’ s “Acrid” Theory |
| DOI：10.16466/j.issn1005-5509.2023.12.005 |
| 中文关键词: 玄府 肺癌 叶天士 “辛味”理论 辛味药 辛味补虚 辛味通滞 |
| 英文关键词: Xuanfu lung cancer YE Tianshi “acrid” theory acrid drugs acridity tonifies deficiency acridity promotes stagnation |
| 基金项目:国家中医药管理局中医药国际合作专项(0610-2240NF021547)；国家自然科学基金青年项目(81703961) |
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| 中文摘要: |
| [目的] 以玄府为视角，探究肺癌发生、发展的病机，探讨叶天士“辛味”理论辨治肺癌的理论依据及临床意义。[方法] 根据玄府相关理论，从玄府开阖失司、“玄府-络脉”失和、“玄府气液”失用等三方面，探讨其对肺癌发生发展转移的影响。通过阅读清代医家叶天士的《临证指南医案》，归纳叶氏“辛味”理论及其对积聚的辨治经验，并附验案一则以佐证。[结果] 玄府开阖失司、络脉失和、气液失用，机体正气虚损，气滞、血瘀、痰毒交相影响，引致肺癌发生、发展；叶天士治疗积聚善用辛味药，其主张辛能祛风、行气、化痰、破癥、补虚。验案所举之老年患者，正虚玄滞而肺癌复发，证属正虚气滞、痰瘀互结，故予“辛味之法”治之，复查肺癌得以减轻。[结论] 叶天士“辛味”理论可通过调节玄府开阖辨治肺癌，适用于肺癌诊治的不同阶段，值得临床推广。 |
| 英文摘要: |
| [Objective] To explore the pathogenesis of lung cancer from the perspective of Xuanfu， and to analyze the theoretical basis and clinical significance of YE Tianshi’s acrid theory in the treatment of lung cancer. [Methods] According to the theory of Xuanfu， this paper discussed its influence on the occurrence， development and metastasis of lung cancer from three aspects: the loss of opening and closing of Xuanfu， the loss of “Xuanfu-collaterals” and the loss of “Xuanfu Qi-liquid”. By reading YE Tianshi’s A Guide to Clinical Practice with Medical Records， YE Tianshi’s “acrid” theory and its differentiation and treatment experiences for cancer were summarized， and demonstrated it with a medical record. [Results] Xuanfu opening and closing loss， collaterals loss， Qi and liquid loss， the body’s healthy Qi deficiency， Qi stagnation， blood stasis， phlegm and toxin interaction， led to the occurrence and development of lung cancer; YE Tianshi was good at using acrid drugs in the treatment of cancer， and advocated that acrid drugs could dispel wind， move Qi， dissolve phlegm， break concretions and tonify deficiency. In the elderly patients mentioned in the medical records， lung cancer recurred due to deficiency of Qi and stagnation of Xuanfu， phlegm and blood stasis. Therefore， the treatment of acridity was given， and lung cancer was alleviated. [Conclusion] YE Tianshi’ s “acrid” theory is suitable for different stages of lung cancer treatment by regulating the opening and closing of Xuanfu， which is worthy of clinical promotion. |
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