| 瞿思颖,涂明琦,王涵芝,等.抑郁症穴位敏化现象与规律探析[J].浙江中医药大学学报,2023,47(12):1413-1422, 1429. |
| 抑郁症穴位敏化现象与规律探析 |
| Analysis on the Phenomenon and Regularity of Acupoint Sensitization for Major Depressive Disorder |
| DOI：10.16466/j.issn1005-5509.2023.12.006 |
| 中文关键词: 抑郁症 穴位敏化 现象 规律 文献计量学 数据挖掘 |
| 英文关键词: major depressive disorder acupoint sensitization phenomenon regularity bibliometrics data mining |
| 基金项目:浙江省中医药现代化专项计划项目(2022ZX010)；浙江省医药卫生科技计划项目(2023KY883) |
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| 中文摘要: |
| [目的] 通过文献计量学和数据挖掘技术探究抑郁症(major depressive disorder，MDD)患者穴位敏化现象和规律，以期为MDD的临床诊疗提供科学思路。[方法] 检索八大数据库和一本中医典籍，将MDD穴位敏化有关的文献收集汇总成数据表，利用文献计量学及数据挖掘技术，对MDD穴位敏化现象和规律进行总结，并就MDD穴位敏化规律进行理论探析。[结果] 共纳入文献29篇，涉及热敏、化学敏、痛敏等多种敏化类型和检测手段；MDD常见敏化穴位是百会，且百会和内关、百会和太冲常同时出现敏化；敏化穴位和敏化类型可分为4个有效聚类群；敏化频次最多的经脉是督脉；敏化穴位主要集中在头面颈项部。[结论] MDD存在多种穴位敏化类型，但研究成果有限；研究发现多个穴位、经脉及部位存在敏化现象；高频敏化穴位和穴位配伍与目前治疗所用穴位基本相同；不同穴位敏化类型不尽相同，这可能与MDD病因病机、伴随症状等相关。 |
| 英文摘要: |
| [Objective] To explore the phenomenon and regularity of acupoint sensitization for major depressive disorder(MDD) based on bibliometric methodology and data mining technology， and to provide scientific ideas for the clinical diagnosis and treatment of MDD. [Methods] Eight?electronic?databases and one ancient book were comprehensively searched and available literature was retrieved. Bibliometric methodology and data mining technology were applied to summarize the phenomenon and regularity of acupoint sensitization for MDD， and?to?explore?the?related theoretical?mechanisms. [Results] A total of 29 literature related to acupoint sensitization of MDD was included. Acupoint sensitization of MDD involved in multiple forms， including heat sensitization， chemical sensitization， pain sensitization， and so on， and the testing?means were diverse. The most common sensitized acupoint was Baihui(GV20). Among these acupoints， sensitization often simultaneously occurred in Baihui(GV20) and Neiguan(PC7)， Baihui(GV20) and Taichong(LR3). The acupoints and sensitization could be divided into 4 effective clusters. The meridian involved with high sensitization frequency was governor vessel. Sensitization mainly occurred in the?head-face-neck?area. [Conclusion] The sensitization phenomenon of MDD has many types， However， there are few related studies at present. The phenomenon of acupoint sensitization involving acupoint， meridians， and location are relatively broad. There might be a close relationship between high-frequency sensitized acupoints and common acupoints for clinical treatment， which may be related to the effect of different acupoints and the etiology and pathogenesis of MDD. |
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