| 廖春满,张正媚,王梅杰,等.2000至 2023年雷公藤多苷研究热点及趋势的可视化分析[J].浙江中医药大学学报,2024,48(7):872-880. |
| 2000至 2023年雷公藤多苷研究热点及趋势的可视化分析 |
| Visual Analysis of Research Hotspots and Trends of Tripterygium Glycosides from 2000 to 2023 |
| DOI：10.16466/j.issn1005-5509.2024.07.019 |
| 中文关键词: 雷公藤多苷 研究热点 研究趋势 可视化分析 VOSviewer CiteSpace 知识图谱 |
| 英文关键词: tripterygium glycosides research hotspots research trends visual analysis VOSviewer CiteSpace knowledge graph |
| 基金项目:2020年北京市中医药科技发展资金项目(JJ-2020-42) Fund project: 2020 Beijing Traditional Chinese Medicine Technology Development Fund Project(JJ-2020-42) |
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| 中文摘要: |
| [目的]梳理雷公藤多苷(tripterygium glycosides，TG)的研究现状与热点，为今后 TG的深入研究与临床推广提供参考依据。 [方法]计算机检索中国知网(China National Knowledge Internet，CNKI)、万方数据库、中文科技期刊数据库(China Science and Technology Journal Database，VIP)、中国生物医学文献数据库(China Biology Medicine disc，CBM)中 2000年 1月至 2023年 6月关于 TG的文献，使用 NoteExpress软件进行数据合并、查重及清洗，采用 Excel构建年度发文量折线图，运用 VOSviewer 1.6.13软件和 CiteSpace 6.2 R2软件对其作者、机构及 |
| 英文摘要: |
| [Objective] To summarize the research status and hotspots of tripterygium glycosides(TG)，to provide reference basis for future in-depth research and clinical promotion of TG. [Methods] Computer retrieval of literature related to TG from January 2000 to June 2023 wasconducted using the China National Knowledge Internet(CNKI)，Wanfang Data，China Science and Technology Journal Database(VIP)， China Biology Medicine disc(CBM). Use NoteExpress software to merge，duplicate check，and clean data，and use Excel software to construct an annual publication volume line chart. Visualize and analyze the author，organization，and Keywords using VOSviewer 1.6.13 and CiteSpace 6.2 R2 software，and draw relevant graphs. [Results] A total of 1 752 articles were included. Since 2008，the number of publications has shown a decreasing trend in recent years after a gradual increase. A total of 4 186 authors were involved，including 75 core authors，forming a collaborative team represented by DING Ying，LI Zhenbin，LIN Na，CUI Ruiqin，CHEN Weidong and others. The main publishing institutions were the First Affiliated Hospital of He’nan University of Chinese Medicine and He’nan University of Chinese Medicine，followed by Dongzhimen Hospital of Beijing University of Chinese Medicine. The research institutions were relativelyindependent and scattered，mostly through cooperation between traditional Chinese medicine universities and their affiliated hospitals， with less cross regional cooperation. A total of six clusters of Keywords had been formed in the network diagram. The research focuses weremainly summarized as the clinical research on the application of TG combination drugs in kidney diseases such as diabetes nephropathy， purpura nephritis and nephrotic syndrome，rheumatic immune diseases such as rheumatoid arthritis，skin and mucosal diseases，and the experimental research on the toxicity and side effects of TG. In recent years，Keywords that had emerged included dermatitis，eczema， mizolastin，inflammatory factors，immune function，tacrolimus，and so on. [Conclusion]The clinical efficacy and safety research of TG in kidney diseases，rheumatic immune diseases and other fields are hot topics. Dermatitis，eczema，and other skin and mucosal diseases，as well as the mechanism of TG action and inflammatory factors，may be the future research trends. There is still a need to strengthen cooperation among teams，strengthen basic research on the mechanism of TG action，and explore effective compatibility and detoxification methods，providing reference basis for the clinical application of TG in the future. |
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