| 陶伟辰,幸冰峰,郑娇蓉,等.基于数据挖掘探析广东省名中医洪敏教授治疗失眠用药规律[J].浙江中医药大学学报,2024,48(8):973-981. |
| 基于数据挖掘探析广东省名中医洪敏教授治疗失眠用药规律 |
| Analysis of Professor HONG Min’s Medication Rules for Treating Insomnia Based on Data Mining |
| DOI：10.16466/j.issn1005-5509.2024.08.012 |
| 中文关键词: 失眠 数据挖掘 中医传承辅助平台 用药规律 聚类分析 关联规则 名医经验 |
| 英文关键词: insomnia data mining Traditional Chinese Medicine Inheritance Support System Platform medication rule cluster analysis association rules experience of famous doctor |
| 基金项目:广东省中医药管理局基金项目(20213013)；广东省自然科学基金项目(22201910240002422) |
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| 中文摘要: |
| [目的] 探讨广东省名中医洪敏教授治疗失眠的用药规律。[方法] 收集整理洪敏教授临床治疗失眠的处方，使用中医传承辅助平台，对处方的用药频次、四气五味归经以及组方规律、潜在新方等进行数据挖掘和分析。[结果] 收集筛选出方剂共509条，中药共180味，使用频次前5位的中药依次为炒酸枣仁、法半夏、炙甘草、茯苓、黄芩，高频药物组合有法半夏-炒酸枣仁、炙甘草-法半夏、法半夏-茯苓、炙甘草-炒酸枣仁、茯苓-炒酸枣仁、法半夏-黄芩、陈皮-茯苓等，并得到7个潜在新方组合。[结论] 洪敏教授治疗失眠用药以疏肝安神、清热燥湿、健脾化痰为主，临床中注重五运六气思想结合六经辨证理论，并善于灵活运用脏腑补泻理论，多脏并调，注重结合体质、运气、病机，司人、司天、司病，综合调治，使阴阳调和，失眠得愈。 |
| 英文摘要: |
| [Objective] To explore the medication rules of Professor HONG Min， a famous traditional Chinese medicine practitioner in Guangdong Province， for treating insomnia. [Methods] The prescriptions of Professor HONG Min for treating insomnia in clinical practice were collected and sorted out， and data mining and analysis were conducted on the frequency of medication， four properties， five flavors， meridian tropism， prescription patterns， potential new formulas and so on by using the Traditional Chinese Medicine Inheritance Support System Platform. [Results] A total of 509 formulas and 180 Chinese herbs were screened out. The top five Chinese herbs in terms of frequency of use were Semen Ziziphi Spinosae Preparata， Rhizoma Pinelliae Preparatum， Radix Glycyrrhizae Preparata， Poria cocos and Radix Scutellariae. The high-frequency herb combinations included Rhizoma Pinelliae Preparatum-Semen Ziziphi Spinosae Preparata， Radix Glycyrrhizae Preparata-Rhizoma Pinelliae Preparatum， Rhizoma Pinelliae Preparatum-Poria cocos， Radix Glycyrrhizae Preparata-Semen ziziphi spinosae Preparata， Poria cocos-Semen ziziphi spinosae Preparata， Rhizoma Pinelliae Preparatum-Radix Scutellariae， Citri Reticulatae Pericarpium-Poria cocos and so on. Seven potential new formula combinations were also obtained. [Conclusion] Professor HONG Min’s treatment of insomnia is mainly based on soothing the liver and calming the mind， clearing heat and drying dampness， strengthening the spleen and resolving phlegm. In clinical practice， she pays attention to the theory of five movements and six Qi combined with the theory of six meridians differentiation. She is good at flexibly applying the theory of Zang fu tonification and purgation， balancing multiple organs simultaneously. She also pays attention to integrating constitution， movement of Qi， pathogenesis， human nature， heaven nature and disease nature， comprehensively regulating and treating them to achieve harmony between Yin and Yang and curing insomnia. |
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