| 邵诗思,钦丹萍.胡柚皮化学成分和药理作用研究进展[J].浙江中医药大学学报,2025,49(2):214-222. |
| 胡柚皮化学成分和药理作用研究进展 |
| Research Progress on Chemical Components and Pharmacological Action of Peels of Citrus Paradisi cv. Changshan Huyou |
| DOI：10.16466/j.issn1005-5509.2025.02.014 |
| 中文关键词: 胡柚皮 黄酮 柚皮苷 新橙皮苷 挥发油 药理作用 止咳祛痰 胃肠运动 |
| 英文关键词: peels of Citrus paradisi cv. Changshan huyou flavonoids naringin neohesperidin volatile oil pharmacological action relieving cough and expelling phlegm gastrointestinal motility |
| 基金项目:浙江省“尖兵”“领雁”研发攻关计划项目(2023C02058)；浙江省钦丹萍名老中医专家传承工作室项目(GZS2020020) |
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| 中文摘要: |
| [目的] 综述胡柚皮化学成分、药理作用的研究进展，推进胡柚皮中药开发和临床应用。[方法] 检索1994至2024年中国知网、万方、PubMed、Web of Science和Google Scholar等数据库中胡柚皮化学成分、药理活性及临床应用相关的研究报道，归纳总结胡柚皮的研究现状。[结果] 现代研究表明，胡柚皮中含有多种生理活性成分，包括黄酮类化合物、柠檬苦素类化合物、香豆素类化合物、挥发油类化合物、酚酸类化合物、果胶、膳食纤维、类胡萝卜素等，具有抗氧化、抗菌、降血脂、降血糖、调节免疫、调节胃肠运动、保肝护肝、止咳祛痰等药理作用。目前胡柚皮的临床研究较少，偶有应用胡柚皮治疗呼吸系统疾病与运动系统疾病的文献报道。[结论] 胡柚皮具有丰富的功能性化学成分、广泛的药理作用和一定的药用价值，随着研究的不断深入，胡柚皮在传统医药、临床应用及保健食品等方面的开发和利用将有着广阔的前景。 |
| 英文摘要: |
| [Objective] To summarize the research progress on the chemical constituents and pharmacological actions of Peels of Citrus paradisi cv. Changshan huyou， and promote traditional medicine and clinical applications development of Peels of Citrus paradisi cv. Changshan huyou. [Methods] The research reports on chemical composition， pharmacological activity and clinical application of Peels of Citrus paradisi cv. Changshan huyou were retrieved from CNKI， Wanfang， PubMed， Web of Science and Google Scholar databases from 1994 to 2024， and the research status of Peels of Citrus paradisi cv. Changshan huyou was summarized. [Results] Modern studies have shown that peels of Citrus paradisi cv. Changshan huyou contains a variety of physiological active ingredients， including flavonoids， limonins， coumarins， volatile oils， phenolic acids， pectin， dietary fiber， carotenoids， etc. It has pharmacological effects such as anti-oxidation， antibacterial， lowering blood lipids， lowering blood sugar， regulating immune， regulating gastrointestinal movement， protecting the liver， relieving cough and expelling phlegm， etc. At present， clinical research on peels of Citrus paradisi cv. Changshan huyou is relatively scarce， with occasional reports in using it to treat respiratory and musculoskeletal system diseases. [Conclusion] Peel of Citrus paradisi cv. Changshan huyou has rich functional chemical components， extensive pharmacological effects and certain medicinal values. As research on peels of Citrus paradisi cv. Changshan huyou continues to delve deeper， its development and utilization in traditional medicine， clinical applications and health food products hold promising prospects. |
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