| 郑智朝,郑茗泽,刘雨佳,等.从“因郁致渴”理论探讨经方治疗抑郁症继发2型糖尿病的证治方药[J].浙江中医药大学学报,2025,49(2):235-240. |
| 从“因郁致渴”理论探讨经方治疗抑郁症继发2型糖尿病的证治方药 |
| Discussion on the Treatment Formulas of Classical Prescriptions for Treating Type-2 Diabetes Secondary to Depression from the Theory of “Thirst Caused by Depression” |
| DOI：10.16466/j.issn1005-5509.2025.02.017 |
| 中文关键词: 《黄帝内经》 《金匮要略》 抑郁症 2型糖尿病 经方 郁证 消瘅 证治方药 |
| 英文关键词: Huangdi Neijing Jingui Yaolue depression type-2 diabetes classical prescriptions depressive syndrome Xiaodan treatment formulas |
| 基金项目:浙江省自然科学基金探索青年项目(LQ24H270013);浙江省中医药科技计划青年人才支持计划项目(2024ZR102);浙江中医药大学校级科研基金项目(2022RCZXZK17) |
|
| 摘要点击次数: 84 |
| 全文下载次数: 73 |
| 中文摘要: |
| [目的] 以《黄帝内经》中“因郁致渴”理论为基础，梳理中医典籍中的相关条文，探讨经方防治抑郁症继发2型糖尿病的证治方药。[方法] 基于《黄帝内经》中“因郁致渴”理论，运用文献研究的方法梳理《金匮要略》《诸病源候论》《神农本草经》等古代文献中关于郁证和消瘅病因、病机及其病传的理论支撑。在此基础上探讨郁证继发消瘅的机制，以及经方防治抑郁症继发2型糖尿病的证治方药，并附一验案以佐证。[结果] “郁证”之“脏气弱”与“消瘅”的“五脏柔弱”阶段，有共同基础病机，其病理进程与抑郁症继发2型糖尿病的过程类似。即“脏气弱”之郁证，气郁日久、火热渐盛则可发展为消瘅一病，在此基础上依据“津虚—气郁—化热”的病机衍化顺序，可以将抑郁症继发2型糖尿病整个病理过程分为“初期—进展期—末期”三个阶段予以辨证治疗。所附验案为火热滞气伤津型郁症，治以泻热养津、理气解郁，方用百合散加减，取得较好疗效。[结论] 抑郁症继发2型糖尿病的初期以津血亏虚为主，治以甘滋补津，方药可参照百合地黄汤。进展期以气郁为主，兼有津虚，治以理气解郁、稍佐甘滋，方药可参考柴胡百合汤。末期火热内盛，治疗以泻热救津为主，根据气郁之有无分别以栝楼牡蛎散、百合散为代表方剂。 |
| 英文摘要: |
| [Objective] To explore the prevention and treatment of type-2 diabetes(T2DM) secondary to depression by using classical formulas， based on the theory of “thirst induced by depression” as described in the Huangdi Neijing， and systematically review relevant texts in traditional Chinese medicine literature. [Methods] Utilizing the “thirst induced by depression” theory from the Huangdi Neijing， this study employs literature research to analyze ancient texts such as Jingui Yaolue， Zhubing Yuanhou Lun and Shennong Bencao Jing for theoretical support regarding the causes， pathogenesis and transmission of depressive syndromes and consumption disorders. This foundation allows for an exploration of the mechanisms through which depressive syndromes lead to consumption and the therapeutic strategies for managing T2DM secondary to depression in clinical practice. Finally， a test case was attached to support it. [Results] The concept of “Yin syndrome” characterized by “weakened organ Qi” shares a common pathological basis with “consumption”， particularly during the “weakened five organs” stage. The pathological progression is similar to that seen in the development of T2DM secondary to depression. Specifically， the “Yin syndrome” associated with “weakened organ Qi” may evolve into a consumption syndrome due to prolonged Qi stagnation and increasing heat. Therefore， based on the pathological sequence of “fluid deficiency—Qi stagnation—heat transformation”， the entire pathological process of depression leading to T2DM can be categorized into three stages for diagnosis and treatment: “early stage—progressive stage—end stage”. The attached test case was of hot Qi stagnation and fluid injury type depression， treated to relieve heat for notifying fluid， clearing Qi and relieving depression， administered with revised Lily Powder and achieved good curative effect. [Conclusion] In the early stage of depression leading to T2DM， the primary condition is fluid and blood deficiency， treated by nourishing fluids， with reference to the Baihe Dihuang Decoction. During the progressive stage， Qi stagnation predominates alongside fluid deficiency， treated by regulating Qi and resolving stagnation， with references to the Chaihu Baihe Decoction. In the end stage， characterized by internal heat， the treatment focuses on clearing heat and nourishing fluids， with representative formulas including Guolou Muli San and Baihe San， depending on the presence or absence of Qi stagnation. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |